This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: FLJ23741; fork head-related protein like B; Forkhead box protein P1; Forkhead-related transcription factor 1; glutamine-rich factor 1; Mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551
Gene Aliases: 12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FOXP1; hFKH1B; HSPC215; MFH; QRF1