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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 216 and 279 of Human FRAT1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29145 targets FRAT1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29145 immunogen is synthetic peptide corresponding to a region within amino acids 216 and 279 of Human FRAT1.
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FRAT-1; frequently rearranged in advanced T-cell lymphomas 1; proto-oncogene FRAT1