|Immunocytochemistry (ICC)||20 µg/ml|
|Immunofluorescence (IF)||20 ug/ml|
|Western Blot (WB)||0.5-1 ug/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 15 amino acid peptide near the carboxy terminus of human FREM1.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is K562 cell lysate.
PA5-20981 can be used with blocking peptide PEP-1095.
FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: extracellular matrix protein QBRICK; FRAS1-related extracellular matrix protein 1; Protein QBRICK; RP11-265B7.2, BNAR, C9orf143, C9orf145, C9orf154, MOTA, TILRR
Gene Aliases: BC037594; BNAR; C9orf143; C9orf145; C9orf154; crf11; D430009N09; D630008K06; eye<m02Jus>; eyes2; FREM1; heb; MOTA; qbrick; TILRR; TRIGNO2
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