Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cap methyltransferase 1; Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; Cap1 2'O-ribose methyltransferase 1; CMTR1; FtsJ methyltransferase domain containing 2; FtsJ methyltransferase domain-containing protein 2; FTSJD2; hMTr1; Interferon-stimulated gene 95 kDa protein; ISG95; KIAA0082; MTr1; S-adenosyl-L-methionine-dependent methyltransferase FTSJD2
Gene Aliases: 1300018I05Rik; AI451264; CMTR1; FTSJD2; hMTr1; KIAA0082; mKIAA0082; MTR1