This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: SQGRKDIVEA SSQKGRRGLG LTLRGFDQEL NVDWRDEPEP SACEQVSWFP ECTTEIPDTQ EMSDWMVVGK RKMIIEDETE FCGEELLHSV LQCK
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cap methyltransferase 1; Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; Cap1 2'O-ribose methyltransferase 1; FtsJ methyltransferase domain containing 2; FtsJ methyltransferase domain-containing protein 2; Interferon-stimulated gene 95 kDa protein; ISG95; MTr1; S-adenosyl-L-methionine-dependent methyltransferase FTSJD2
Gene Aliases: 1300018I05Rik; AI451264; CMTR1; FTSJD2; hMTr1; KIAA0082; LRRG00129; mKIAA0082; MTR1; RGD1307801