This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.
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Protein Aliases: DNA helicase V; far upstream element (FUSE) binding protein 1; far upstream element (FUSE) binding protein 4; Far upstream element-binding protein 1; FBP; FUSE binding protein 1; FUSE-binding protein 1; hDH V
Gene Aliases: 9530027K12Rik; D3Ertd330e; FBP; FUBP; FUBP1; Fubp4; hDH V
UniProt ID: (Human) Q96AE4
Molecular Function: RNA metabolism protein