Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: TEQVELPGP GQWVVAECPA RVDFSGGWSD TPPLAYELGG AVLGLAVRVD GRRPIGARAR RIPEPELWLA VGPRQDEMTV KIVCRCLADL RDYCQPHAPG ALLKAAFICA GIVHVHSELQ LSEQLLRTFG GGFELHTWSE LPHGSGLGTS SILAGTALAA LQRAAGRVVG TEALIHAVLH LEQVLTTGGG WQDQVGGLMP GIKVGRSRAQ LPLKVEVEEV TVPEGFVQKL NDHLLLVYTG KTRLARNLLQ DVLRSWYARL PAVVQNAHSL VRQTEECAEG FRQGSLPLLG QCLTSYWEQK KLMAPGCEPL TVRRMMDVLA PHVHGQSLAG AGGGGFLYLL TKEPQQKEAL EAVLAKTEGL GNYSIHLVEV DTQGLSLKLL GTEASTCCPF P (695-1084 aa encoded by BC032542)
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fucokinase; L-fucose kinase; mFLJ00241 protein; UNQ5838
Gene Aliases: 1110046B12Rik; AI303278; FCSK; FUK
UniProt ID: (Human) Q8N0W3, (Mouse) Q7TMC8
Entrez Gene ID: (Human) 197258, (Mouse) 234730, (Rat) 307848
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