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Immunofluorescent analysis of MDA-MB231 cells using a FUS polyclonal antibody (Product # PA5-23696) at a dilution of 1:10-50. Primary antibody was detected with goat anti-rabbit lgG, fluor-conjugated secondary antibody (green). Actin filaments have been labeled with red dye conjugated phalloidin.
|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 499-526 amino acids from the C-terminal region of human FUS|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine based on sequence homology.
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
75 kDa DNA-pairing protein; ALS6; fus-like protein; FUS1; fused in sarcoma; fusion gene in myxoid liposarcoma; fusion, derived from t(12;16) malignant liposarcoma; heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; HNRNPP2; oncogene FUS; oncogene TLS; pigpen protein; POMP75; protein pigpen; RNA-binding protein FUS; TLS; translocated in liposarcoma; translocated in liposarcoma protein
ALS6; D430004D17Rik; D930039C12Rik; ETM4; FUS; FUS1; HNRNPP2; POMP75; TLS