FUT4 (Fucosyltransferase 4) is a Protein Coding gene. Diseases associated with FUT4 include Colon Adenocarcinoma and Liver Lymphoma. Among its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Mannose type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include fucosyltransferase activity and alpha-(1->3)-fucosyltransferase activity. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
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Protein Aliases: 3-fucosyl-N-acetyl-lactosamine epitope; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; alpha (1,3) fucosyltransferase, myeloid specific; alpha (1,3) fucosyltransferase, myeloid-specific; alpha 1,3-fucosyltransferase; alpha 1,3-fucosyltransferase Fuc-T (similar to mouse Fut4); alpha 13-fucosyltransferase Fuc-T (similar to mouse Fut4); Alpha-(1,3)-fucosyltransferase 4; ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; Fuc-TIV; Fucosyltransferase 4; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); Fucosyltransferase IV; fucT-IV; Galactoside 3-L-fucosyltransferase; Lewis X; stage-specific embryonic antigen 1
Gene Aliases: AI451562; CD15; ELFT; FAL; FCT3A; FUC-TIV; Fuct; FucT-IV; FUT4; FUTIV; LeX; SSEA-1; Ssea1
Molecular Function: glycosyltransferase