This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: LRTDIDATCT PRRASSNQRG LNQIWNVKKQ SVYLMNLRKS GTLGHPGSLD ETTYERLAEE TLDSLAEFFE DLADKPYTFE DYDVSFGSGV LTVKLGGDLG TYVINKQTPN KQIWLSSPSS GPKRYDWTGK NWVYSHDGVS LHELLAAELT KALKTKLDLS SLAYSGKDA; Positive Samples: K-562, U-87MG, Jurkat, Raji, DU-145, Mouse kidney, Mouse liver, Mouse heart; Cellular Location: Cytoplasm, Mitochondrion
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: d-FXN; Frataxin intermediate form; Frataxin mature form; Frataxin(56-210); Frataxin(78-210); Frataxin(81-210); Frataxin, mitochondrial; Friedreich ataxia; Friedreich ataxia protein; Fxn; i-FXN; m56-FXN; m78-FXN; m81-FXN
Gene Aliases: CyaY; FA; FARR; FRDA; FXN; RGD1565754; X25