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Invitrogen

FXN Polyclonal Antibody

View all (27) FXN antibodies
635D49A6-4B57-425E-8DC4-6BA1AEB7B473 Created with sketchtool. Datasheet
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Product Details

Tested Applications
Dilution
Western Blot (WB)
1:500 - 1:2000
Product Specifications
Species Reactivity
Human, Mouse
Host / Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant funsion protein containing a sequence corresponding to amino acids 42-210 of human FXN.
Conjugate
Unconjugated
Form
Liquid
Concentration
2.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen sequence: LRTDIDATCT PRRASSNQRG LNQIWNVKKQ SVYLMNLRKS GTLGHPGSLD ETTYERLAEE TLDSLAEFFE DLADKPYTFE DYDVSFGSGV LTVKLGGDLG TYVINKQTPN KQIWLSSPSS GPKRYDWTGK NWVYSHDGVS LHELLAAELT KALKTKLDLS SLAYSGKDA; Positive Samples: K-562, U-87MG, Jurkat, Raji, DU-145, Mouse kidney, Mouse liver, Mouse heart; Cellular Location: Cytoplasm, Mitochondrion

Target Information

FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: d-FXN; Frataxin intermediate form; Frataxin mature form; Frataxin(56-210); Frataxin(78-210); Frataxin(81-210); Frataxin, mitochondrial; Friedreich ataxia; Friedreich ataxia protein; Fxn; i-FXN; m56-FXN; m78-FXN; m81-FXN

Gene Aliases: CyaY; FA; FARR; FRDA; FXN; X25

UniProt ID: (Human) Q16595, (Mouse) O35943

Entrez Gene ID: (Human) 2395, (Mouse) 14297

Molecular Function: cation transporter kinase transferase transporter

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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