Proteintech

FXYD6 Polyclonal Antibody

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FXYD6 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human spleen using 15805-1-AP (FXYD6 antibody) at dilution of 1:100 (under 40x lens).

FXYD6 Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 15805-1-AP (FXYD6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

FXYD6 Antibody in Flow Cytometry (Flow) — 1X10^6 SH-SY5Y cells were stained with 0.2ug FXYD6 antibody (15805-1-AP, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L) with dilution 1:1000.

Product Details

15805-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:3,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Flow Cytometry (Flow)	0.2 µg/1x10^6 cells	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	FXYD6 Fusion Protein Ag8538 (23-95 aa encoded by BC018652) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.19 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: KEKEMDPFH YDYQTLRIGG LVFAVVLFSV GILLILSRRC KCSFNQKPRA PGDEEAQVEN LITANATEPQ KAEN (23-95 aa encoded by BC018652)

Target Information

This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FXYD domain-containing ion transport regulator 6; Phosphohippolin; PLM-like protein; Vascular endothelial cell-specific protein 6; VESP6

Gene Aliases: 0610030I18Rik; FXYD6; Php; Plp; UNQ521/PRO1056

UniProt ID: (Human) Q9H0Q3, (Mouse) Q9D164, (Rat) Q91XV6

Entrez Gene ID: (Human) 53826, (Mouse) 59095, (Rat) 63847

Molecular Function: primary active transporter