PA5-29855 targets Frizzled 1 in WB applications and shows reactivity with Human samples.
The PA5-29855 immunogen is recombinant protein fragment corresponding to a region within amino acids 113 and 372 of Human Frizzled 1.
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Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
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Protein Aliases: Drosophila; frizzled; 1; frizzled 1; frizzled 1, seven transmembrane spanning receptor; frizzled family receptor 1; frizzled homolog 1; frizzled, Drosophila, homolog of, 1; Frizzled-1; Fz-1; FzE1; hFz1; homolog of; seven transmembrane spanning receptor; Wnt receptor
Gene Aliases: FZD1
UniProt ID: (Human) Q9UP38
Entrez Gene ID: (Human) 8321