Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Dog, Bat, Bovine (100%).
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
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Protein Aliases: Chfz-1; Dfrizzled-1; Frizzled 1; frizzled 1, seven transmembrane spanning receptor; Frizzled family receptor 1; Frizzled homolog 1; frizzled, Drosophila, homolog of, 1; Frizzled-1; Fz receptor 1; Fz-1; Fz1; FZD1; FzE1; HFz1; Rfz1; Wnt receptor; Xfrizzled-1
Gene Aliases: FZD1
UniProt ID: (Human) Q9UP38
Entrez Gene ID: (Human) 8321