Invitrogen

FZD3 Polyclonal Antibody

View all (10) FZD3 antibodies

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FZD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of formalin-fixed paraffin-embedded human skeletal muscle using a FZD3/Frizzled 3 polyclonal antibody (Product # PA5-33552). Heat-induced antigen retrieval was performed prior to staining.

FZD3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of formalin-fixed paraffin-embedded human skin using a FZD3/Frizzled 3 polyclonal antibody (Product # PA5-33552). Heat-induced antigen retrieval was performed prior to staining.

Product Details

PA5-33552

Applications	Tested Dilution	Publications
Immunohistochemistry (Paraffin) (IHC (P))	3-5 µg/mL	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic 18 amino acid peptide from N-terminal extracellular domain of human FZD3 / Frizzled 3. View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS
Contains	0.1% sodium azide
Storage conditions	Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
RRID	AB_2550932

Product Specific Information

In IHC applications, antigen retrieval using Proteinase K treatment is recommended.

Target Information

This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3; Frizzled-3; Fz-3; hFz3

Gene Aliases: Fz-3; FZD3

UniProt ID: (Human) Q9NPG1

Entrez Gene ID: (Human) 7976

Molecular Function: transmembrane signal receptor

establishment of planar polarity neuron migration neural tube closure hair follicle development positive regulation of neuroblast proliferation G-protein coupled receptor signaling pathway Wnt signaling pathway, calcium modulating pathway neuron differentiation cell proliferation in midbrain non-canonical Wnt signaling pathway post-anal tail morphogenesis dopaminergic neuron axon guidance serotonergic neuron axon guidance inner ear morphogenesis negative regulation of mitotic cell cycle, embryonic canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway sympathetic ganglion development commissural neuron axon guidance negative regulation of execution phase of apoptosis midbrain morphogenesis

Process(es)

G-protein coupled receptor activity protein binding Wnt-protein binding PDZ domain binding Wnt-activated receptor activity