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Proteintech
FZD5 Polyclonal Antibody
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Product Details
21519-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FZD5 Fusion Protein Ag16082 (524-585 aa encoded by BC114346)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GKTVESWRR FTSRCCCRPR RGHKSGGAMA AGDYPEASAA LTGRTGPPGP AATYHKQVSL SHV (524-585 aa encoded by BC114346)
Target Information
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZP434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; unnamed protein product; Wnt receptor
Gene Aliases: C2orf31; FZD5; HFZ5; MCOPCB11
UniProt ID: (Human) Q13467
Entrez Gene ID: (Human) 7855
embryonic axis specification
angiogenesis
eye development
vasculature development
glandular epithelial cell maturation
positive regulation of T cell cytokine production
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
synapse assembly
negative regulation of cell proliferation
anterior/posterior axis specification, embryo
Wnt signaling pathway
neuron differentiation
embryonic camera-type eye development
post-embryonic camera-type eye development
positive regulation of interferon-gamma production
positive regulation of interleukin-1 beta production
positive regulation of tumor necrosis factor production
T cell differentiation in thymus
non-canonical Wnt signaling pathway
positive regulation of transcription from RNA polymerase II promoter
embryonic camera-type eye morphogenesis
system development
Spemann organizer formation
canonical Wnt signaling pathway
apoptotic process involved in morphogenesis
intestinal epithelial cell maturation
branching involved in labyrinthine layer morphogenesis
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
labyrinthine layer blood vessel development
chorionic trophoblast cell differentiation
cellular response to molecule of bacterial origin
regulation of chorionic trophoblast cell proliferation
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
regulation of bicellular tight junction assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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