Invitrogen

FZD5 Polyclonal Antibody

View all (8) FZD5 antibodies

Questions & Answers

Questions & Answers

Product Image Gallery

FZD5 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis of FZD5 in human synovium tissue (rheumatoid arthritis) using FZD5 Polyclonal Antibody (Product # PA1-32554). Antigen retrival : Heat-induced antigen retrieval.

Product Details

PA1-32554

Applications	Tested Dilution	Publications
Immunohistochemistry (Paraffin) (IHC (P))	19 µg/mL	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic 16 amino acid peptide from N-terminal extracellular domain of human Frizzled 5 View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS
Contains	0.1% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2263220

Product Specific Information

PA1-32554 detects Frizzled 5 from human samples.

Target Information

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: DKFZp434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; Wnt receptor

Gene Aliases: C2orf31; FZD5; HFZ5

UniProt ID: (Human) Q13467

Entrez Gene ID: (Human) 7855

Molecular Function: transmembrane signal receptor

embryonic axis specification angiogenesis positive regulation of T cell cytokine production G-protein coupled receptor signaling pathway Wnt signaling pathway, calcium modulating pathway synapse assembly negative regulation of cell proliferation anterior/posterior axis specification, embryo neuron differentiation post-embryonic camera-type eye development positive regulation of interferon-gamma production T cell differentiation in thymus non-canonical Wnt signaling pathway positive regulation of JUN kinase activity Wnt signaling pathway involved in dorsal/ventral axis specification positive regulation of transcription from RNA polymerase II promoter cell maturation embryonic camera-type eye morphogenesis Spemann organizer formation canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway apoptotic process involved in morphogenesis branching involved in labyrinthine layer morphogenesis syncytiotrophoblast cell differentiation involved in labyrinthine layer development labyrinthine layer blood vessel development chorionic trophoblast cell differentiation regulation of canonical Wnt signaling pathway cellular response to molecule of bacterial origin regulation of chorionic trophoblast cell proliferation regulation of mitophagy positive regulation of protein targeting to mitochondrion beta-catenin destruction complex disassembly regulation of bicellular tight junction assembly

Process(es)

beta-amyloid binding G-protein coupled receptor activity protein binding Wnt-protein binding protein kinase binding ubiquitin protein ligase binding Wnt-activated receptor activity