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Product Details
PA5-75512
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 167-212 of Human FZD6.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2719240
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 6; frizzled 6, seven transmembrane spanning receptor; frizzled family receptor 6; frizzled homolog 6; Frizzled-6; Frizzled6; Fz-6; FZD-6; mFz6; seven transmembrane helix receptor
Gene Aliases: FZ-6; FZ6; FZD6; HFZ6; NDNC10
UniProt ID: (Human) B4DRN0, (Mouse) Q61089
Entrez Gene ID: (Human) 8323, (Mouse) 14368, (Rat) 282581
establishment of planar polarity
neural tube closure
hair follicle development
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
platelet activation
cell proliferation in midbrain
non-canonical Wnt signaling pathway
embryonic nail plate morphogenesis
inner ear morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
midbrain morphogenesis
signal transduction
cell surface receptor signaling pathway
multicellular organism development
nervous system development
Wnt signaling pathway
midbrain development
canonical Wnt signaling pathway
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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