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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
FZR1 Fusion Protein Ag9201 (216-493 aa encoded by BC013413) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.22 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: TSQVTRLCD LSVEGDSVTS VGWSERGNLV AVGTHKGFVQ IWDAAAGKKL SMLEGHTARV GALAWNAEQL SSGSRDRMIL QRDIRTPPLQ SERRLQGHRQ EVCGLKWSTD HQLLASGGND NKLLVWNHSS LSPVQQYTEH LAAVKAIAWS PHQHGLLASG GGTADRCIRF WNTLTGQPLQ CIDTGSQVCN LAWSKHANEL VSTHGYSQNQ ILVWKYPSLT QVAKLTGHSY RVLYLAMSPD GEAIVTGAGD ETLRFWNVFS KTRSTKESVS VLNLFTRIR (216-493 aa encoded by BC013413)
FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC20 homolog 1; CDC20-like 1b; CDC20-like protein 1; Cdh1/Hct1 homolog; cell division cycle 20 related 1; Fizzy-related protein homolog; Fzr; hCDH1
Gene Aliases: AW108046; CDC20C; CDH1; FYR; FZR; FZR1; FZR2; HCDH; HCDH1; KIAA1242
UniProt ID: (Human) Q9UM11, (Mouse) Q9R1K5
Entrez Gene ID: (Human) 51343, (Mouse) 56371, (Rat) 314642
Molecular Function:
ubiquitin-protein ligase
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