Proteintech

FZR1 Polyclonal Antibody

View all (8) FZR1 antibodies

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FZR1 Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of ( -20°C Ethanol) fixed HepG2 cells using 16368-1-AP (FZR1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

FZR1 Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of (10% Formaldehyde) fixed HeLa cells using 16368-1-AP (FZR1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

FZR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver tissue slide using 16368-1-AP ( FZR1 antibody) at dilution of 1:200 (under 10x lens).

FZR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver tissue slide using 16368-1-AP ( FZR1 antibody) at dilution of 1:200 (under 40x lens).

FZR1 Antibody in Western Blot (WB) — Mouse liver tissue were subjected to SDS PAGE followed by western blot with 16368-1-AP (FZR1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Western Blot (WB) — Mouse heart tissue were subjected to SDS PAGE followed by western blot with 16368-1-AP (FZR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Western Blot (WB) — NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 16368-1-AP (FZR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Western Blot (WB) — Jurkat cells were subjected to SDS PAGE followed by western blot with 16368-1-AP (FZR1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 16368-1-AP ( FZR1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Western Blot (WB) — HepG2 cells were subjected to SDS PAGE followed by western blot with 16368-1-AP (FZR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 16368-1-AP (FZR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Western Blot (WB) — C6 cells were subjected to SDS PAGE followed by western blot with 16368-1-AP (FZR1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

FZR1 Antibody in Immunoprecipitation (IP) — IP result of anti-FZR1 (IP:16368-1-AP, 4ug; Detection:16368-1-AP 1:500) with mouse heart tissue lysate 3200ug.

Product Details

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC)

1:50-1:500

-

Immunofluorescence (IF)

1:50-1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

-

Immunoprecipitation (IP)

0.5-4.0 µg

-

Western Blot (WB)

1:500-1:2000

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Product Specifications

Species

Human, Mouse, Rat

Published species

Mouse

Expression System

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FZR1 Fusion Protein Ag9201

Conjugate

Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Target Information

FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: CDC20 homolog 1; CDC20-like 1b; CDC20-like protein 1; Cdh1/Hct1 homolog; cell division cycle 20 related 1; Fizzy-related protein homolog; Fzr; hCDH1

Gene Aliases: AW108046; CDC20C; CDH1; FYR; FZR; FZR1; FZR2; HCDH; HCDH1; KIAA1242

UniProt ID: (Human) Q9UM11, (Mouse) Q9R1K5

Entrez Gene ID: (Human) 51343, (Mouse) 56371, (Rat) 314642

Molecular Function: enzyme modulator

DNA repair mitotic nuclear division positive regulation of cell proliferation anaphase-promoting complex-dependent catabolic process G2 DNA damage checkpoint regulation of meiotic nuclear division protein ubiquitination involved in ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle lens fiber cell differentiation protein K11-linked ubiquitination negative regulation of cell aging positive regulation of ubiquitin protein ligase activity cellular response to DNA damage stimulus cell cycle

Process(es)

protein binding anaphase-promoting complex binding ubiquitin-protein transferase activator activity