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Invitrogen
FZR1 Polyclonal Antibody
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FZR1 Antibody (34-2000) in IHC
International journal of molecular sciences 2020 -
Association of APC/C Cdh1 and PAH in HCC. ( A ) Expression box plot showing significant differential expression of Cdh1 in normal vs. tumor tissues using normal-tumor matched liver cancer patient RNAseq data from TCGA. p value < 0.05 was considered to be statistically significant. ( B ) Expression box plot showing significant differential expression of PAH in normal vs. tumor tissues using normal-tumor matc... View More
Product Details
34-2000
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
C. elegans,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the C-terminus of human FZR protein
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
FZR is a 7WD domain family member implicated in cell cycle regulation of Drosophila and yeast. It has been shown that the over expression of fzr proteins increases natural killer cell-mediated cell death and as a result, suppresses tumor growth. The fzr protein is essential for cyclosome activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CDC20 homolog 1; CDC20-like 1b; CDC20-like protein 1; Cdh1/Hct1 homolog; cell division cycle 20 related 1; Fizzy-related protein homolog; Fzr; hCDH1
Gene Aliases: AW108046; CDC20C; CDH1; FYR; FZR; FZR1; FZR2; HCDH; HCDH1; KIAA1242
UniProt ID: (Human) Q9UM11, (Mouse) Q9R1K5
Entrez Gene ID: (Human) 51343, (Mouse) 56371
DNA repair
mitotic nuclear division
positive regulation of cell proliferation
anaphase-promoting complex-dependent catabolic process
G2 DNA damage checkpoint
regulation of meiotic nuclear division
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of protein catabolic process
cell division
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
lens fiber cell differentiation
protein K11-linked ubiquitination
negative regulation of cell aging
positive regulation of ubiquitin protein ligase activity
cellular response to DNA damage stimulus
cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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