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Nordic
Factor I Polyclonal Antibody
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Product Details
SHAHU-FI
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Human Factor I
Conjugate
Form
Lyophilized
Purification
IgG Fraction
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at 4 C, not refrozen, and preferably used the same day.
In immunoelectrophoresis use 2 µL serum or equivalent against 120 µL antiserum. In double radial immunodiffusion (Ouchterlony) use a rosette arrangement with 10 µL antiserum in 3 mm diameter center well and 2 µL serum samples (neat and serially diluted in 2 mm diameter peripheral wells. Different bleedings of the immunized animals are pooled to obtain a broad spectrum balanced against the varying concentrations of the individual serum protein components.
Reconstitute the lyophilized antiserum by adding 1 mL sterile distilled water.
Species Reactivity: The antiserum does not cross-react with any other Human plasma proteins as tested in gel diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.
Target Information
Factor I, a serine protease, is a regulatory component of both the alternative and the classical complement pathway. Factor I is synthesized as a single chain precursor of 88 kDa, processed to yield the active form, composed of two disulfide-linked chains, the a-chain (50 kDa) and the b-chain (38 kDa). Plasma concentration is 35 µg/mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C3b-inactivator; C3B/C4B inactivator; CFI; complement component I; complement control protein factor I; Complement factor I; complement factor I heavy chain; factor i; Konglutinogen-activating factor; light chain of factor I; prepro-C3b/C4B inactivator; unnamed protein product
Gene Aliases: AHUS3; ARMD13; C3b-INA; C3BINA; CFI; FI; IF; KAF
UniProt ID: (Human) P05156
Entrez Gene ID: (Human) 3426
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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