|Tested species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Factor IX from human plasma.|
|Storage buffer||0.01M HEPES, pH 7.4, with 50% glycerol, 0.15M NaCl|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Inhibition Assays (IA)||Assay Dependent|
|Immunoelectrophoresis (IE)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-74094 detects Factor IX from human samples.
PA1-74094 has been successfully used in ELISA, immunoelectrophoresis, and inhibition assay applications.
The PA1-74094 immunogen is Factor IX from human plasma.
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.