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Product Details
14384-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fascin Fusion Protein Ag5816 (1-187 aa encoded by BC000521)
Conjugate
Form
Liquid
Concentration
0.22 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTANGTAEA VQIQFGLINC GNKYLTAEAF GFKVNASASS LKKKQIWTLE QPPDEAGSAA VCLRSHLGRY LAADKDGNVT CEREVPGPDC RFLIVAHDDG RWSLQSEAHR RYFGGTEDRL SCFAQTVSPA EKWSVHIAMH PQVNIYSVTR KRYAHLSARP ADEIAVDRDV PWGVDSLITL AFQDQRYS (1-187 aa encoded by BC000521)
Target Information
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; Fascin; fascin 1; Fascin homolog 1; fascin homolog 1, actin-bundling protein; Fascin1; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein
Gene Aliases: AI663989; FAN1; fascin-1; FSCN1; HSN; p55; SNL
UniProt ID: (Human) Q16658, (Mouse) Q61553
Entrez Gene ID: (Human) 6624, (Mouse) 14086
cell-cell junction assembly
cell proliferation
anatomical structure morphogenesis
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
cell-cell adhesion
actin filament organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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