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Invitrogen
Fascin Polyclonal Antibody
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Product Details
PA5-95983
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Amount
69 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FIGCRKVTGT LDANRSSYDV FQLEFNDGAY NIKDSTGKYW TVGSDSAVTS SGDTPVDFFF EFCDYNKVAI KVGGRYLKGD HAGVLKASAE TVDPASLWEY; Positive Samples: U-251MG, HeLa, NCI-H460, HepG2, SH-SY5Y, Mouse brain, Mouse spinal cord; Cellular Location: Cell junction, Cell projection, Cytoplasm, cytoskeleton, cytosol, filopodium, invadopodium, microvillus
Target Information
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; epididymis secretory sperm binding protein; Fascin; fascin 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin-bundling protein; Fascin1; fscn1 {ECO:0000250|UniProtKB:Q16658}; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein; unnamed protein product
Gene Aliases: AI663989; FAN1; Fascin; fascin-1; FSCN1; HSN; p55; SNL
UniProt ID: (Human) Q16658, (Rat) P85845, (Mouse) Q61553
Entrez Gene ID: (Human) 6624, (Rat) 683788, (Mouse) 14086
actin filament organization
cell-cell junction assembly
establishment or maintenance of cell polarity
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
parallel actin filament bundle assembly
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
liver development
cellular response to cell-matrix adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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