Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This affinity-purified antibody is directed against human Fbp5A protein. A BLAST analysis was used to suggest cross reactivity with Fbp5A protein from human and chimpanzee based on 100% homology with the immunizing sequence. Expect partial reactivity with Fbp5A from dog based on partial (~92%, 13/14) sequence homology. Reactivity against homologues from other sources is not known.
F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
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Protein Aliases: Early mitotic inhibitor 1; F-box only protein 5; F-box protein Fbx5
Gene Aliases: EMI1; FBX5; Fbxo31; FBXO5
UniProt ID: (Human) Q9UKT4
Entrez Gene ID: (Human) 26271