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Fabgennix
Ferritin Polyclonal Antibody
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Product Details
FRTN-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length Ferritin Protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. Ferritin is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in the light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. The ferritin gene has multiple pseudogenes, and ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis. Ferritin is a holoenzyme shell with a molecular weight of about 450 kDa, and consists of 24 subunits of two types, H(heavy) and L(light), and capable of storing up to 4,500 atoms of ferric iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: apoferritin; Cell proliferation-inducing gene 15 protein; epididymis secretory sperm binding protein; Ferritin H subunit; Ferritin heavy chain; ferritin heavy chain 1; ferritin heavy subunit; Ferritin L subunit; Ferritin L subunit 1; ferritin L-chain; Ferritin light chain; Ferritin light chain 1; ferritin light polypeptide-like 3; ferritin light subunit; Ferritin subunit H; ferritin, heavy polypeptide 1; ferritin, light polypeptide; frih; fril; FTL; H-ferritin; iron ion binding; iron-binding; immunosuppressor; growth factor; L apoferritin; MGC71996; PIG15; placenta immunoregulatory factor; proliferation-inducing protein 15; unnamed protein product
Gene Aliases: FHC; FTH; FTH1; FTHL6; FTL; Ftl-1; FTL1; HFE5; HFt; L-ferritin; LFTD; MFH; NBIA3; NBIA9; OK/SW-cl.84; PIG15; PLIF
UniProt ID: (Human) P02794, (Human) P02792, (Mouse) P09528, (Rat) P19132, (Rat) P02793
Entrez Gene ID: (Human) 2495, (Human) 2512, (Mouse) 14319, (Rat) 25319, (Mouse) 14325, (Rat) 29292
iron ion transport
cellular iron ion homeostasis
immune response
negative regulation of cell proliferation
negative regulation of fibroblast proliferation
negative regulation of ferroptosis
intracellular sequestering of iron ion
oxidation-reduction process
negative regulation of necrotic cell death
response to lead ion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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