This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Recommended positive controls: 293T, H1299, Molt-4, Neuro2A, PC-12, A549, A549 nuclear extract, Jurkat, Jurkat nuclear extract, SK-N-SH, SK-N-SH nuclear extract, IMR32, IMR32 nuclear extract.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (89%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Nop1p / Fibrillarin was originally identified as a nucleolar protein of bakers yeast, Saccharomyces cerevisiae (accession P15646). The Nop1p protein is essential for yeast viability and is localized in the nucleoli. The human homologue of Nop1p is fibrillarin (accession P22087) a component of the nucleolar small nuclear ribonucleoprotein (snRNP) particle. The human fibrillarin gene is located on chromosome 19 (19q13. 1).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 34 kDa nucleolar scleroderma antigen; 34-kD nucleolar scleroderma antigen; Histone-glutamine methyltransferase; Nucleolar protein 1; RNA, U3 small nucleolar interacting protein 1; rRNA 2'-O-methyltransferase fibrillarin; U6 snRNA 2'-O-methyltransferase fibrillarin
Gene Aliases: AL022665; FBL; FIB; FIB1; FLRN; RNU3IP1
Molecular Function: RNA processing factor