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Proteintech
Fibrinogen alpha chain Polyclonal Antibody
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Product Details
20645-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fibrinogen alpha chain Fusion Protein Ag9567 (20-218 aa encoded by BC020764)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ADSGEGDFL AEGGGVRGPR VVERHQSACK DSDWPFCSGE DWNYKCPSGC RMKGLIDEVN QDFTNRINKL KNSLFEYQKN NKDSHSLTTN IMEILRGDFS SANNRDNTYN RVSEDLRSRI EVLKRKVIEK VTANNLLVAR VTTEETPHLK ARAIKWQMRP EVKPIMKEHI APREAMLNLA LSEVSTLLLW GSLPCPPRLS (20-218 aa encoded by BC020764)
Target Information
Fibrinogen is a soluble protein found in blood plasma and is produced by the liver cells. The protein is a hexamer consisting of two sets of disulfide linked chains. Fibrinogen is essential for blood coagulation as the precursor of fibrin. It is converted to fibrin by the action of thrombin in the presence of calcium ions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A-alpha fibrinogen; alpha-fibrinogen; alpha-fibrinogen precursor; extended alpha-E variant; Fibrinogen a chain; Fibrinogen alpha; Fibrinogen alpha chain; Fibrinogen α chain; fibrinogen, A alpha polypeptide; Fibrinogenα chain; unnamed protein product
Gene Aliases: AMYLD2; ENSMUSG00000059807; FGA; Fib; Fib2
UniProt ID: (Human) P02671, (Mouse) E9PV24
Entrez Gene ID: (Human) 2243, (Mouse) 14161
adaptive immune response
immune system process
cell-matrix adhesion
blood coagulation
hemostasis
platelet activation
plasminogen activation
positive regulation of heterotypic cell-cell adhesion
fibrinolysis
induction of bacterial agglutination
innate immune response
positive regulation of vasoconstriction
positive regulation of exocytosis
positive regulation of protein secretion
protein polymerization
response to calcium ion
protein-containing complex assembly
positive regulation of ERK1 and ERK2 cascade
platelet aggregation
blood coagulation, common pathway
blood coagulation, fibrin clot formation
positive regulation of peptide hormone secretion
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of blood coagulation, common pathway
negative regulation of endothelial cell apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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