Positive Control: Human skin tissue, JAR, SiHa, SKOV-3, rat testis tissue, mouse ovary tissue.
Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dance; Developmental arteries and neural crest EGF-like protein; FIBL-5; Fibulin-5; FLJ90059; testis tissue sperm-binding protein Li 75n; UP50; Urine p50 protein
Gene Aliases: ADCL2; ARCL1A; ARMD3; DANCE; EVEC; FBLN5; FIBL-5; HNARMD; UNQ184/PRO210; UP50
UniProt ID: (Human) Q9UBX5
Entrez Gene ID: (Human) 10516
Molecular Function: extracellular matrix structural protein