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Search Thermo Fisher Scientific
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide derived from human Ficolin 2/Ficolin B, amino acids 231-313. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 50% glycerol, 1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
-20°C |
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 37 kDa elastin-binding protein; Collagen/fibrinogen domain-containing protein 2; EBP-37; ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin); ficolin B; Ficolin-2; Ficolin-B; Ficolin-beta; Hucolin; L-ficolin; RP11-263F14.2; Serum lectin p35
Gene Aliases: EBP-37; FCN2; FCNL; ficolin-2; P35
UniProt ID: (Human) Q15485
Entrez Gene ID: (Human) 2220
Molecular Function:
intercellular signal molecule
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