This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: KEPGEYAVHI MCDDEDIKDS PYMAFIHPAT GGYNPDLVRA YGPGLEKSGC IVNNLAEFTV DPKDAGKAPL KIFAQDGEGQ RIDIQMKNRM DGTYACSYTP VKAIKHTIAV VWG
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABP-278; ABP-280 homolog; ABP-280-like protein; actin binding protein 278; Actin-binding-like protein; Beta-filamin; Fh1; filamin B, beta; Filamin homolog 1; filamin, beta; Filamin-3; Filamin-B; FilaminB; FLN-B; Larsen syndrome 1 (autosomal dominant); Thyroid autoantigen; Truncated ABP; Truncated actin-binding protein
Gene Aliases: ABP-278; ABP-280; AL024016; AOI; FH1; FLN-B; FLN1L; FLN3; FLNB; LRS1; SCT; TABP; TAP