|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 89 and 344 of Human Filensin|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29976 targets Filensin in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29976 immunogen is recombinant fragment corresponding to a region within amino acids 89 and 344 of Human Filensin.
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin (or CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 115 KD; Beaded filament structural protein 1; beaded filament structural protein 1, filensin; CP115; cytoskeletal protein; cytoskeletal protein, 115 KD; Filensin; Lens fiber cell beaded-filament structural protein CP 115; Lens intermediate filament-like heavy; LIFL-H
Gene Aliases: BFSP1; CP115; CP94; CTRCT33; LIFL-H
UniProt ID: (Human) Q12934
Entrez Gene ID: (Human) 631
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