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      Flotillin 1 Polyclonal Antibody

      See 3 other Flotillin 1 antibodies ›
      Flotillin 1 Polyclonal Antibody for Western Blot

      Catalog#: PA5-17127 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-17127 100 µL
      275.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

      Anti-Rabbit Secondary Antibodies (264)
      Alexa Fluor® Anti-Rabbit Secondary Antibodies (69)
      HRP Anti-Rabbit Secondary Antibodies (30)

      Product Details

      References

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human, Mouse, Non-human primate, Rat
      Published species reactivity Mouse
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen Synthetic peptide corresponding residue surrounding Ile368 of human flotillin-1
      Conjugate Unconjugated
      Form Liquid
      Purification Antigen affinity chromatography
      Storage buffer 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol
      Contains no preservative
      Storage Conditions -20°C
      Tested Applications Dilution *
      Western Blot (WB) 1:1000

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Published Applications
      Immunohistochemistry - Free Floating (IHC (Free)) See 1 publications below

      Product Specific Information

      It is not recommended to aliquot this antibody.

      Background/Target Information

      Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      References

      Immunohistochemistry - Free Floating

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Mouse Not Cited Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.
      PA5-17127 was used in immunohistochemistry - free floating to investigate the mechanisms by which anti-Tau antibodies alleviate Alzheimer's disease in mice       		Collin L,Bohrmann B,Göpfert U,Oroszlan-Szovik K,Ozmen L,Grüninger F Brain : a journal of neurology (137:2834) 2014

      Bioinformatics

      Protein Aliases:

      Flotillin-1; integral membrane component of caveolae; OTTHUMP00000164855; REG-2; Reggie-2

      Gene Aliases:

      FLOT1; Rareg; Reg2; reggie-2

      UniProt ID:

      (Human) O75955, (Mouse) O08917, (Rat) Q9Z1E1

      Entrez Gene ID:

      (Human) 10211, (Mouse) 14251, (Rat) 64665

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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