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|Tested species reactivity||Human, Mouse, Non-human primate, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding residue surrounding Ile368 of human flotillin-1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry - Free Floating (IHC (Free))||See 1 publications below|
It is not recommended to aliquot this antibody.
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.
PA5-17127 was used in immunohistochemistry - free floating to investigate the mechanisms by which anti-Tau antibodies alleviate Alzheimer's disease in mice
|Collin L,Bohrmann B,Göpfert U,Oroszlan-Szovik K,Ozmen L,Grüninger F||Brain : a journal of neurology (137:2834)||2014|
Flotillin-1; integral membrane component of caveolae; OTTHUMP00000164855; REG-2; Reggie-2
FLOT1; Rareg; Reg2; reggie-2