The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
FLCN is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in FLCN are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of FLCN results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BHD; BHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome protein; Birt-Hogg-Dube syndrome protein homolog; FLCN; Folliculin
Gene Aliases: AU014660; B430214A04Rik; BHD; FLCL; FLCN