PA5-27351 targets FYN in IF and WB applications and shows reactivity with Human samples.
The PA5-27351 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 227 of Human FYN.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
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Protein Aliases: c-syn protooncogene; FYN oncogene related to SRC, FGR, YES; OKT3-induced calcium influx regulator; p59-FYN; Proto-oncogene c-Fyn; Proto-oncogene Syn; SLK; Src-like kinase; src/yes-related novel; SYN; tyrosine kinase p59fyn(T); Tyrosine-protein kinase Fyn
Gene Aliases: FYN; p59-FYN; SLK; SYN
UniProt ID: (Human) P06241
Entrez Gene ID: (Human) 2534