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      G3BP1 Polyclonal Antibody

      See 4 other G3BP1 antibodies ›
      G3BP1 Polyclonal Antibody for Western Blot, IF, ICC and IHC (P)

      Catalog#: PA5-29455 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-29455 100 µL
      349.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

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      Product Details

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen Recombinant protein fragment corresponding to a region within amino acids 147 and 466 of Human G3BP1
      Conjugate Unconjugated
      Form Liquid
      Concentration 1 mg/ml
      Purification Antigen affinity chromatography
      Storage buffer PBS, pH 7, with 20% glycerol
      Contains 0.01% thimerosal
      Storage Conditions -20° C, Avoid Freeze/Thaw Cycles
      Tested Applications Dilution *
      Immunocytochemistry (ICC) Assay-Dependent
      Immunofluorescence (IF) Assay-Dependent
      Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
      Western Blot (WB) 1:1000-1:10,000

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Product Specific Information

      PA5-29455 targets G3BP1 in IHC (P) and WB applications and shows reactivity with Human samples.

      The PA5-29455 immunogen is recombinant protein fragment corresponding to a region within amino acids 147 and 466 of Human G3BP1.

      Background/Target Information

      This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      Bioinformatics

      Protein Aliases:

      ATP-dependent DNA helicase VIII; DNA helicase VIII; G3BP; G3BP-1; GAP binding protein; GAP SH3 domain-binding protein 1; GTPase activating protein (SH3 domain) binding protein 1; hDH VIII; Ras GTPase-activating protein-binding protein 1; Ras-GTPase-activating protein SH3-domain-binding protein; RasGAP-associated endoribonuclease G3BP

      Gene Aliases:

      G3BP; G3BP1; HDH-VIII

      UniProt ID:

      (Human) Q13283

      Entrez Gene ID:

      (Human) 10146

      Molecular Function:

      RNA binding protein nucleic acid binding signaling molecule

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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