Peptide sequence: NLVFKWILFG QRPYWWVLDT DYYSNTSVPL IKQFPVTCET GPGSPSGHAM
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 93%; Sheep: 100%
Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: catalytic subunit; G-6-Pase; G6Pase; G6Pase-alpha; G6PC1; G6PT; Glc-6-Pase-alpha; Glucose-6-phosphatase; Glucose-6-phosphatase alpha; glucose-6-phosphatase catalytic subunit; glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease); glucose-6-phosphatase, catalytic subunit; GSD1; GSD1a; MGC163350
Gene Aliases: AW107337; BOS_19118; G6Pase; G6PC; G6PC1; G6PT; Glc-6-Pase; GSD1; GSD1a