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Proteintech
G6PD Polyclonal Antibody
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Product Details
25413-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
G6PD Fusion Protein Ag21862 (1-515 aa encoded by BC000337)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Amount
64.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAEQVALSR TQVCGILREE LFQGDAFHQS DTHIFIIMGA SGDLAKKKIY PTIWWLFRDG LLPENTFIVG YARSRLTVAD IRKQSEPFFK ATPEEKLKLE DFFARNSYVA GQYDDAASYQ RLNSHMNALH LGSQANRLFY LALPPTVYEA VTKNIHESCM SQIGWNRIIV EKPFGRDLQS SDRLSNHISS LFREDQIYRI DHYLGKEMVQ NLMVLRFANR IFGPIWNRDN IACVILTFKE PFGTEGRGGY FDEFGIIRDV MQNHLLQMLC LVAMEKPAST NSDDVRDEKV KVLKCISEVQ ANNVVLGQYV GNPDGEGEAT KGYLDDPTVP RGSTTATFAA VVLYVENERW DGVPFILRCG KALNERKAEV RLQFHDVAGD IFHQQCKRNE LVIRVQPNEA VYTKMMTKKP GMFFNPEESE LDLTYGNRYK NVKLPDAYER LILDVFCGSQ MHFVRSDELR EAWRIFTPLL HQIELEKPKP IPYIYGSRGP TEADELMKRV GFQYEGTYKW VNPHKL (1-515 aa encoded by B C000337)
Target Information
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; G6PD; Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate dehydrogenase variant A- (EC 1.1.1.49); unnamed protein product
Gene Aliases: CNSHA1; G6PD; G6PD1
UniProt ID: (Human) P11413
Entrez Gene ID: (Human) 2539
glucose metabolic process
pentose-phosphate shunt
lipid metabolic process
cholesterol biosynthetic process
NADP metabolic process
NADPH regeneration
glutathione metabolic process
pentose-phosphate shunt, oxidative branch
response to iron(III) ion
pentose biosynthetic process
substantia nigra development
response to food
cellular response to oxidative stress
erythrocyte maturation
regulation of neuron apoptotic process
response to ethanol
ribose phosphate biosynthetic process
glucose 6-phosphate metabolic process
negative regulation of cell growth involved in cardiac muscle cell development
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
negative regulation of reactive oxygen species metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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