Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:5,000 | View 4 publications 4 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Immunoprecipitation (IP) |
Assay-dependent | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
G6PD Fusion Protein Ag21862 (1-515 aa encoded by BC000337) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.43 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MAEQVALSR TQVCGILREE LFQGDAFHQS DTHIFIIMGA SGDLAKKKIY PTIWWLFRDG LLPENTFIVG YARSRLTVAD IRKQSEPFFK ATPEEKLKLE DFFARNSYVA GQYDDAASYQ RLNSHMNALH LGSQANRLFY LALPPTVYEA VTKNIHESCM SQIGWNRIIV EKPFGRDLQS SDRLSNHISS LFREDQIYRI DHYLGKEMVQ NLMVLRFANR IFGPIWNRDN IACVILTFKE PFGTEGRGGY FDEFGIIRDV MQNHLLQMLC LVAMEKPAST NSDDVRDEKV KVLKCISEVQ ANNVVLGQYV GNPDGEGEAT KGYLDDPTVP RGSTTATFAA VVLYVENERW DGVPFILRCG KALNERKAEV RLQFHDVAGD IFHQQCKRNE LVIRVQPNEA VYTKMMTKKP GMFFNPEESE LDLTYGNRYK NVKLPDAYER LILDVFCGSQ MHFVRSDELR EAWRIFTPLL HQIELEKPKP IPYIYGSRGP TEADELMKRV GFQYEGTYKW VNPHKL (1-515 aa encoded by B C000337)
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G6PD; Glucose-6-phosphate 1-dehydrogenase
Gene Aliases: G6PD; G6PD1
UniProt ID: (Human) Q16000
Entrez Gene ID: (Human) 2539
Molecular Function:
dehydrogenase
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