This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-29662 targets G6PD in ELISA and WB applications and shows reactivity with Human samples.
The PA5-29662 immunogen is recombinant fragment corresponding to a region within amino acids 100 and 322 of Human G6PD.
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This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: G6PD; G6PD1; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase
Gene Aliases: G28A; G6PD; G6pd-1; G6PD1; G6pdx; Gpdx