Keep as concentrated solution.
Predicted reactivity: Rat (90%), Rabbit (89%), Sheep (89%), Rhesus Monkey (98%), Bovine (89%).
Positive Control: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G6PD; Glucose-6-phosphate 1-dehydrogenase
Gene Aliases: G6PD; G6PD1
UniProt ID: (Human) P11413
Entrez Gene ID: (Human) 2539