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          • Primary Antibodies ›
          • GABRA2 Antibodies

          Osenses

          GABA(A) R alpha-2 Polyclonal Antibody

          2 References
          View all (20) GABRA2 antibodies

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          Cite GABA(A) R alpha-2 Polyclonal Antibody

          GABA(A) R alpha-2 Polyclonal Antibody

          Product Details

          OSG00088W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from aa region 350-450 of human GABA(A) R alpha-2 conjugated to an immunogenic carrier protein was used as the antigen
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          Specificity of this antibody: GABRA2.

          Target Information

          GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: FLJ97076; GABA(A) receptor; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; GABAAR subunit alpha-2; GABAARalpha2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid A receptor alpha 2; gamma-aminobutyric acid receptor A2 subunit; Gamma-aminobutyric acid receptor subunit alpha-2

          View more View less

          Gene Aliases: C630048P16Rik; Gabra-2; GABRA2

          View more View less

          UniProt ID: (Human) P47869, (Mouse) P26048

          View more View less

          Entrez Gene ID: (Human) 2555, (Mouse) 14395, (Rat) 289606

          View more View less

          Function(s)
          GABA-A receptor activity benzodiazepine receptor activity GABA-gated chloride ion channel activity ion channel activity extracellular ligand-gated ion channel activity chloride channel activity ligand-gated ion channel
          Process(es)
          regulation of neurotransmitter levels neurotransmitter transport gamma-aminobutyric acid signaling pathway ion transmembrane transport chloride transmembrane transport transport ion transport chloride transport chemical synaptic transmission
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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