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GABBR2 Antibody (PA5-28340) in IHC (F)
Immunohistochemistry (Frozen) analysis of GABBR2 was performed in frozen sectioned E13.5 Rat brain tissue using GABBR2 Polyclonal Antibody (Product # PA5-28340) at a dilution of 1:250 (Green). Red: beta Tubulin 3/ TUJ1, a mature neuron marker, stained by beta Tubulin 3/ TUJ1 antibody diluted at 1:500. Blue: Fluoroshield with DAPI.
Product Details
PA5-28340
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 163 and 516 of Human GABA B Receptor 2
Conjugate
Form
Liquid
Concentration
0.83 mg/mL
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545816
Product Specific Information
Recommended positive controls: U87-MG, unboiled Myc-DDK-tagged Gabbr2-transfected 293T.
Predicted reactivity: Mouse (97%), Rat (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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