Immunogen sequence: AEASAPLSNS SETPVVATEE VVTAESVDGA IQQVVSSGGQ QVITIVTDGI QLGNLHSIPT SGIGQPIIVT MPDGQQVLTV PATDIAEETV ISEEPPAKRQ CIEIIENRVE SAEIEEREAL QKQLDEANRE AQKYRQQLLK KEQEAEAYRQ KLEAMTRLQT NKEAV; Positive Samples: MCF7, HepG2, BT-474, HT-29, Mouse spleen, Mouse thymus; Cellular Location: Nucleus
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
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Protein Aliases: GA binding protein subunit beta1; GA binding protein transcription factor beta subunit 1 transcript variant gamma-2; GA binding protein transcription factor, beta subunit 1; GA-binding protein subunit beta-1; Gabp beta1; GABP subunit beta-1; GABP subunit beta-2; GABPB-2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53
Gene Aliases: BABPB2; E4TF1; E4TF1-47; E4TF1-53; E4TF1B; GABPB; GABPB-1; GABPB-2; GABPB1; GABPB1-1; GABPB1-2; GABPB2; NRF2B1; NRF2B2