Recommended positive controls: GABRA5-transfected 293T.
Predicted reactivity: Mouse (100%), Rat (100%), Bovine (98%).
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GABRA5 is a part of GABA, a major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
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Protein Aliases: GABA(A) receptor subunit alpha-5; GABAA receptor alpha5 subunit; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 5; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5; Gamma-aminobutyric acid receptor subunit alpha-5; ligand-gated ion channel subunit
Gene Aliases: A230018I05Rik; GABRA5