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Invitrogen
GABRB1 Polyclonal Antibody
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Product Details
PA5-40342
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human GABRB1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: VDYKMVSKKV EFTTGAYPRL SLSFRLKRNI GYFILQTYMP STLITILSWV
Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Target Information
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA(A) receptor; GABA(A) receptor subunit beta-1; GABA(A)R beta-1; GABA-RB; GABAAR subunit beta-1; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, beta 1; Gamma-aminobutyric acid receptor subunit beta-1; gamma-aminobutyric acid type A receptor beta1 subunit; GBRB1; unnamed protein product
Gene Aliases: DEE45; EIEE45; GABRB1
UniProt ID: (Human) P18505
Entrez Gene ID: (Human) 2560
transmembrane signaling receptor activity
GABA-A receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
anion channel activity
chloride channel activity
ligand-gated ion channel activity
GABA-gated chloride ion channel activity
neurotransmitter receptor activity
GABA receptor binding
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
ion transport
chloride transport
signal transduction
gamma-aminobutyric acid signaling pathway
response to toxic substance
central nervous system neuron development
response to progesterone
ion transmembrane transport
regulation of membrane potential
ovulation cycle
synaptic transmission, GABAergic
regulation of postsynaptic membrane potential
cellular response to histamine
regulation of presynaptic membrane potential
chloride transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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