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Product Details
OPA1-04111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acid residues specific to the gamma 2 subunit of rat GABRG2 conjugated to KLH
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_325317
Product Specific Information
This antibody is predicted to react with chicken, human, mouse, non-human primate and zebrafish based on 100% sequence homology. The antigenic sequence has no homology with any other GABA-A receptor or alpha and beta subunits.
In Western blot, this antibody detects a ~45 kDa to ~47 kDa protein representing GABA-A receptor gamma 2 in rat brain membranes.
Target Information
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA(A) receptor subunit gamma-2; GABAAR subunit gamma-2; GABRA2; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2; gamma-aminobutyric acid A receptor, gamma 2; Gamma-aminobutyric acid receptor subunit gamma-2
Gene Aliases: GABAA-R; Gabrg-2; Gabrg2; gamma2
UniProt ID: (Mouse) P22723, (Rat) P18508
Entrez Gene ID: (Mouse) 14406, (Rat) 29709
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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