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          • Primary Antibodies ›
          • Glutaminase C (GAC) Antibodies

          Proteintech

          GAC Polyclonal Antibody

          19 References
          View all (4) Glutaminase C (GAC) antibodies

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          Cite GAC Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (19)
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 19

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          GAC Antibody (19958-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using 19958-1-AP (GAC-specific Antibody) at dilution of 1:200 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          GAC Antibody in Western Blot (WB)
          GAC Antibody in Western Blot (WB)
          GAC Antibody in Western Blot (WB)
          GAC Antibody in Western Blot (WB)
          GAC Antibody in Immunoprecipitation (IP)

          Product Details

          19958-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 15 publications 15 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:400
          -

          Immunocytochemistry (ICC/IF)

          -
          View 2 publications 2 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.29 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody is specific to GAC isoform. It has no cross reaction to KGA.

          Target Information

          Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: GLS; glutaminase C; Glutaminase kidney isoform, mitochondrial; glutaminase, phosphate-activated; K-glutaminase; L-glutamine amidohydrolase

          View more View less

          Gene Aliases: 6330442B14; AAD20; AI314027; B230365M23Rik; GAC; GAM; GLS; GLS1; Glut; KGA; KIAA0838; RATGLUT

          View more View less

          UniProt ID: (Human) O94925, (Mouse) D3Z7P3, (Rat) P13264

          View more View less

          Entrez Gene ID: (Human) 2744, (Mouse) 14660, (Rat) 24398

          View more View less

          Function(s)
          glutaminase activity protein binding hydrolase activity hydrolase
          Process(es)
          suckling behavior regulation of respiratory gaseous exchange by neurological system process glutamate biosynthetic process glutamine catabolic process chemical synaptic transmission cellular amino acid biosynthetic process glutamate secretion protein homotetramerization glutamine metabolic process
          It has to be done as per old AB suggested Products section.

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