Immunogen sequence: MTLEEVRGQD TVPESTARMQ GAGKALHELL LSAQRQGCLT AGVYESAKVL NVDPDNVTFC VLAAGEEDEG DIALQIHFTL IQAFCCENDI DIVRVGDVQR LAAIVG
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
GADD45G gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
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Protein Aliases: 17 kD; CR6; Cytokine-responsive protein CR6; DDIT-2; DDIT2; DNA damage-inducible transcript 2 protein; gadd-related protein; gadd-related protein, 17 kD; GADD45-gamma; GADD45gamma; Growth arrest and DNA damage-inducible protein GADD45 gamma; growth arrest and DNA-damage-inducible, gamma; GRP17; RP11-260L6.1
Gene Aliases: CR6; DDIT2; GADD45G; GADD45gamma; GRP17
UniProt ID: (Human) O95257
Entrez Gene ID: (Human) 10912