GAL3ST3 is a member of the galactose-3-O-sulfotransferase protein family. It catalyzes sulfonation by transferring a sulfate group to the 3' position of galactose in N-acetyllactosamine in both type 2 (Gal-beta-1-4GlcNAc-R) oligosaccharides and core-2-branched O-glycans, but not on type 1 or core-1-branched structures. This gene, which has also been referred to as GAL3ST2, is different from the GAL3ST2 gene located on chromosome 2 that encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 3.
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Protein Aliases: Beta-galactose-3-O-sulfotransferase 3; Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3; Gal3ST-3; Gal3ST3; galactose 3'-sulfotransferase; Galactose-3-O-sulfotransferase 3; galbeta1-3GalNAc 3'-sulfotransferase 3; MGC142112; MGC142114
Gene Aliases: GAL3ST-3; GAL3ST2; GAL3ST3