Invitrogen

GALNT2 Polyclonal Antibody

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GALNT2 Polyclonal Antibody

Product Details

PA5-121044

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:100
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 442-571 of human GALNT2 (NP_004472.1).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.08 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2914616

Product Specific Information

Positive test controls include: HeLa, Jurkat, HepG2, mouse lung. The target is usually found in the following locations: Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein.

Immunogen sequence: HQDIAFGALQ QGTNCLDTLG HFADGVVGVY ECHNAGGNQE WALTKEKSVK HMDLCLTVVD RAPGSLIKLQ GCRENDSRQK WEQIEGNSKL RHVGSNLCLD SRTAKSGGLS VEVCGPALSQ QWKFTLNLQQ

Target Information

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: E4TF1B; GABP subunit beta-1; GABP subunit beta-2; GABPB; GABPB-1; GABPB-2; GABPB1; GABPB2; GalNAc-T2; Polypeptide GalNAc transferase 2; Polypeptide N-acetylgalactosaminyltransferase 2; pp-GaNTase 2; ppGaNTase-T2; Protein-UDP acetylgalactosaminyltransferase 2; RP5-956O18.1; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)

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Gene Aliases: AI480629; GalNAc-T2; GALNT2

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UniProt ID: (Human) Q10471, (Mouse) Q6PB93

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Entrez Gene ID: (Human) 2590, (Mouse) 108148, (Rat) 292090

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Function(s)
polypeptide N-acetylgalactosaminyltransferase activity protein binding manganese ion binding carbohydrate binding alpha-1,6-mannosyltransferase activity alpha-1,2-mannosyltransferase activity mannosyltransferase activity alpha-1,3-mannosyltransferase activity alpha-1,3-galactosyltransferase activity UDP-glucose:glycoprotein glucosyltransferase activity glycolipid mannosyltransferase activity oligosaccharyl transferase activity dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity acetylglucosaminyltransferase activity acetylgalactosaminyltransferase activity galactosyltransferase activity fucosyltransferase activity O antigen polymerase activity lipopolysaccharide-1,6-galactosyltransferase activity transferase activity transferase activity, transferring glycosyl groups cellulose synthase activity 9-phenanthrol UDP-glucuronosyltransferase activity 1-phenanthrol glycosyltransferase activity 9-phenanthrol glycosyltransferase activity 1,2-dihydroxy-phenanthrene glycosyltransferase activity phenanthrol glycosyltransferase activity beta-1,4-mannosyltransferase activity alpha-1,2-galactosyltransferase activity dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity lipopolysaccharide-1,5-galactosyltransferase activity dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity inositol phosphoceramide synthase activity glucosyltransferase activity metal ion binding alpha-(1->3)-fucosyltransferase activity alpha-(1->6)-fucosyltransferase activity indole-3-butyrate beta-glucosyltransferase activity salicylic acid glucosyltransferase (ester-forming) activity salicylic acid glucosyltransferase (glucoside-forming) activity benzoic acid glucosyltransferase activity chondroitin hydrolase activity dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity cytokinin 9-beta-glucosyltransferase activity glycosyltransferase
Process(es)
immunoglobulin biosynthetic process protein O-linked glycosylation O-glycan processing protein O-linked glycosylation via serine protein O-linked glycosylation via threonine
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