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Immunogen sequence: RVYNNTLTYGE VRNSKASAYC LDQGAEDGDR AILYPCHGMS SQLVRYSADG LLQL^M
^M
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 95%.
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GalNAc transferase 9; GalNAc-T9; Polypeptide GalNAc transferase 9; Polypeptide N-acetylgalactosaminyltransferase 9; pp-GaNTase 9; Protein-UDP acetylgalactosaminyltransferase 9; UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 9; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
Gene Aliases: GALNAC-T9; GALNACT9; GALNT9
UniProt ID: (Human) Q9HCQ5
Entrez Gene ID: (Human) 50614
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